Recherche

Les médecins en formation au SAR ont la possibilité de participer aux projets de recherches cliniques pour la publication FMH.
La plupart de ces projets de recherche s'effectuent conjointement avec le CHUV et les HUG.

Projets en cours:

Analgesic efficacy of intravenous dexmedetomidine for supraclavicular plexus block: a randomized double-blinded placebo-controlled clinical trial
Interaction between intravenous magnesium sulfate and volatile anesthetics compared to propofol. A three-center prospective randomized single-blinded electrophysiological study

Publications

ESRA Updates - December 2023 | Issue 14 (571 Ko) Patel A, Nouraei SAR. Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE): a physiological method of increasing apnoea time in patients with difficult airways. Anaesthesia 2015 Mar;70(3):323-9. doi: 10.1111/anae.12923. Aitken E, Jackson A, Kearns R, Steven M, Kinsella J, Clancy M, Macfarlane A. Effect of regional versus local anaesthesia on outcome after arteriovenous fistula creation: a randomised controlled trial. Lancet 2016 Sep 10;388(10049):1067-1074. doi: 10.1016/S0140-6736(16)30948-5 Warner MA, Hanson AC, Plimier C, Lee C, Liu VX, Richards T, Kor DR, Roubinian NH. Association between anaemia and hospital readmissions in patients undergoing major surgery requiring postoperative intensive care. Anaesthesia 2022 Sep 8. doi: 10.1111/anae.15859. Sina Grape, MD, MBA Head of Department of Anaesthesia Valais Hospital Sion, Switzerland & Department of Anaesthesia Lausanne University Hospital Lausanne, Switzerland
Risk assessment for major adverse cardiovascular events after noncardiac surgery using self-reported functional capacity: international prospective cohort study (367 Ko) Giovanna A. Lurati Buse1,* , Eckhard Mauermann 2, Daniela Ionescu 3, Wojciech Szczeklik 4,Stefan De Hert 5, Miodrag Filipovic 6, Beatrice Beck-Schimmer 7, Savino Spadaro 8,Purificacion Matute 9, Daniel Bolliger 2, Sanem Cakar Turhan 10, Judith van Waes 11,Filipa Lagarto 12, Kassiani Heodoraki 13 , Anil Gupta14 , Hans-Jorg Gillmann 15 , Luca Guzzetti16 , Katarzyna Kotfis17, Hinnerk Wulf18, Jan Larmann19, Dan Corneci 20, Frederique Chammartin-Basnet 21, Simon J. Howell 22, and the MET: Reevaluation for Perioperative Cardiac Risk investigators Anesthesiology Department University Hospital Du¨ sseldorf, Heinrich Heine University, Du¨ sseldorf, Germany, 2 Clinic for Anaesthesia, Intermediate Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Basel, Switzerland, 3 Department of Anaesthesia and Intensive Care I, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania, 4 Center for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland, 5 Department of Anaesthesiology and Perioperative Medicine, Ghent University Hospital, Ghent University, Ghent, Belgium, 6 Division of Anesthesiology, Intensive Care, Rescue and Pain Medicine, Kantonsspital St. Gallen, St. Gallen, Switzerland, 7 Institute of Anaesthesiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 8 Department of Translational Medicine, University of Ferrara, Ferrara, Italy, 9 Department of Anaesthesia, Hospital Clinic of Barcelona, Universidad de Barcelona, Barcelona, Spain, 10 Department of Anesthesiology and ICU, Ankara University Medical School, Ankara, Turkey, 11 Department of Anesthesiology, University Medical Center Utrecht, Utrecht, the Netherlands, 12 Department of Anesthesiology, Hospital Beatriz Angelo, Loures, Portugal, 13 Aretaieion University Hospital National and Kapodistrian University of Athens, Athens, Greece, 14 Department of Perioperative Medicine and Intensive Care, Karolinska Hospital and Institution for Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden, 15 Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany, 16 Anesthesia and Intensive Care Department, University Hospital, Varese, Italy, 17 Department of Anesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University, Szczecin, Poland, 18 Department of Anesthesiology and Critical Care Medicine, University Hospital Marburg, Marburg, Germany, 19 Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany, 20 Carol Davila University of Medicine and Pharmacy Bucharest Head of Anesthesia and Intensive Care Department I, Central Military Emergency University Hospital “Dr. Carol Davila”, Bucharest, Romania, 21 Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, University of Basel, Basel, Switzerland and 22 Leeds Institute of Medical Research at St James’s, University of Leeds, Leeds, UK
The postoperative analgesic efficacy of liposomal bupivacaine versus long-acting local anaesthetics for peripheral nerve and field blocks (1 Mo) Alexandre Nguyen, Sina Grape, Mattia Gobbetti and Eric Albrecht
Management of adverse effects of intrathecal opioids in acute pain (480 Ko) Sina Grape, Lecturer a, Kariem El-Boghdadly, Consultant, Honorary Senior Lecturer b, c,Eric Albrecht, Professor, Program Director of Regional Anaesthesia & Clinical Research d, * a Department of Anaesthesia, Valais Hospital, Sion, University of Lausanne, Lausanne, Switzerland b Department of Anaesthesia, Guy's and St Thomas' NHS Foundation Trust, United Kingdom c King's College London, London, United Kingdom d Department of Anaesthesia, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland
Management of Adverse Effects of Intrathecal Opioids in Acute Pain (2 Mo) Sina Grape, Lecturer, Kariem El-Boghdadly, Consultant, Honorary Senior Lecturer, Eric Albrecht, Professor
Caduceus Express - Février 2023, Vol. 25; N° 2 (657 Ko) Le « Patient Blood Management » ou la gestion optimale de la transfusion A. Kuonen1, G. Canellini2, 1 Centre Hospitalier du Valais Romand, 2 Institut Central des Hôpitaux, Hôpital du Valais, Sion
The great fluid debate: saline or so-called “balanced” salt solutions? (852 Ko) Maristella Santi 1, Sebastiano A. G. Lava 2, Pietro Camozzi 1, Olivier Giannini 3, Gregorio P. Milani 4, Giacomo D. Simonetti 1,2, Emilio F. Fossali 4, Mario G. Bianchetti 1* and Pietro B. Faré 5
Swiss Latin Airway Guidelines: a holistic approach for improving airway management (3 Mo) Gabriele Casso a, Georges L. Savoldelli b, Christian Balmer c, Patrick Ravussin d, Patrick Schoettker e a Department of Anaesthesiology and Intensive Care, Istituto Cardiocentro EOC, Lugano, Switzerland b Division of Anaesthesiology, Department of Anaesthesiology, Clinical Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Switzerland c Department of Anaesthesiology, Valais Hospital, Sion, Switzerland d Faculty of Biology and Medicine, Lausanne, Switzerland e Department on Anaesthesiology, University Hospital of Lausanne (CHUV), Switzerland
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma. Nat Med. 2021 Feb;27(2):289-300 (2 Mo) Livnat Jerby-Arnon1,2†, Cyril Neftel1,2,3,4†, Marni E. Shore1,2,3, Matthew J. McBride5, Brian Haas1, Benjamin Izar1,6, Hannah R. Weissman1,2,3, Angela Volorio1,3, Gaylor Boulay1,3, Luisa Cironi4, Alyssa R. Richman1,2,3, Liliane C. Broye4, Joseph M. Gurski7, Christina C. Luo3, Ravindra Mylvaganam3, Lan Nguyen1, Shaolin Mei8, Johannes c. Melms6, Christophe Georgescu1, Ofir Cohen1, Jorge E. Buendia-Buendia6, Michael S. Cuoco1, Danny Labes9, Daniel R. Zollinger10, Joseph M. Beechem10, G. Petur Nielsen3, Ivan Chebib7, Gregory Cote11, Edwin Choy11, Igor Letovanec4, Stéphane Cherix12, Nikhil Wagle6, Peter K. Sorger8, Alex B. Haynes13, John T. Mullen13, Ivan Stamenkovic4, Miguel N. Rivera1,3, Cigall Kadoch1,5, Orit Rozenblatt-Rosen1,2, Mario L. Suvà1,2,3‡*, Nicolò Riggi4‡*, Aviv Regev1,2,14,15‡* 1 Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA 2 Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA 3 Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA 4 Institute of Pathology, Faculty of Biology and Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, 1011, Switzerland 5 Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA 6 Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA 7 Massachusetts General Hospital Cancer Center, 55 Fruit Street, Boston, MA, 02114, USA 8 Laboratory for Systems Pharmacology, Harvard Medical School, Boston, MA, 02115, USA 9 Flow Cytometry Facility, Department of Biology and Medicine, University of Lausanne, Lausanne, 10 11, Switzerland 10 NanoString Technologies Inc., 530 Fairview Avenue North, Seattle, WA 98109, USA. 11 Department of Medicine, Division of Hematology and Oncology, Massachusetts General Hospital, Boston, MA, 02114, USA 12 Department of Orthopedics, Faculty of Biology and Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, 1011, Switzerland 13 Department of Surgery, Massachusetts General Hospital, Boston, MA, 02114, USA 14 Howard Hughes Medical Institute, Koch Institute for Integrative Cancer Research, Department of Biology, MIT, Cambridge, MA, 02139, USA 15 Lead contact
Volumineux tératome mature du médiastin antérieur (400 Ko) Sophie Soudry, médecin diplômée*, Liliane Akiki, médecin diplômée*, Jean-Claude Granges, médecin diplômé, PD Dr med. Sina Grape Service d’Anesthésiologie de l’Hôpital de Sion, Hôpital du Valais, Sion
Low‐ versus high‐dose intraoperative opioids: A systematic review with meta‐analyses and trial sequential analyses (1 Mo) Eric Albrecht1 | Sina Grape2 | Jonathan Frauenknecht1 | Laurent Kilchoer1 | Kyle R. Kirkham3
Voice Prosthesis Ingestion Causing Intestinal Perforation: A Case Report (1 Mo) Claudia Benvenuti and Sina Grape* Department of Anesthesia, Hospital of Sion, Av. Grand-Champsec 80, 1951 Sion, Switzerland
Muscle-sparing aortic coarctation repair (2 Mo) Stephanie G. Berset, MD,a Hitendu Dave, MD,b Christian Balmer, MD,b Anna Nowacka,c Raymond Pfister, MD,d Patrick O. Myers, MD,d and René Prêtre, MDd
Syndrome de TURP (186 Ko) Ana Borda de Agua Reis a, c, d, Sina Grape b, c a MD; b MD, PD, MBA; c Service d’Anesthésiologie et de Réanimation du CHVR, Hôpital du Valais, Sion; d Service d’anesthésiologie, CHUV, Lausanne
Sauvetage en conditions difficiles : quelle complémentarité ? (930 Ko) Charpilloz C, Gaegi A, Selz Amaudruz F, Tosetti S, Moser A. Rev Med Suisse. 2022 Aug 17;18(791):1497-1500. doi: 10.53738/REVMED.2022.18.791.1497
Efficacy and safety of intrathecal morphine for analgesia after lower joint arthroplasty: a systematic review and meta-analysis with meta-regression and trial sequential analysis (886 Ko) E. Gonvers,1 K. El-Boghdadly,2,3 S. Grape4 and E. Albrecht5
Retroclavicular vs supraclavicular brachial plexus block for distal upper limb surgery: a randomised, controlled, single-blinded trial (794 Ko) Sina Grape1, Amit Pawa2, Eric Weber1 and Eric Albrecht3,*
Intra-operative analgesia with remifentanil vs. dexmedetomidine: a systematic review and meta-analysis with trial sequential analysis (434 Ko) S. Grape,1 K. R. Kirkham,2 J. Frauenknecht3 and E. Albrecht4
The Analgesic Efficacy of Transversus Abdominis Plane Block After Bariatric Surgery: a Systematic Review and Meta-analysis with Trial Sequential Analysis (958 Ko) Sina Grape1 & Kyle R. Kirkham2 & Eric Albrecht3
Analgesic efficacy of PECS and serratus plane blocks after breast surgery: A systematic review, meta-analysis and trial sequential analysis☆ (1 Mo) Sina Grape a, Eric Jaunina, Kariem El-Boghdadly b,c, Vincent Chand, Eric Albrechte,⁎
Analgesic efficacy of PECS vs paravertebral blocks after radical mastectomy: A systematic review, meta-analysis and trial sequential analysis (561 Ko) Sina Grape (Lecturer) a, Kariem El-Boghdadly (Consultant) b,d, Eric Albrecht (MD, PD-MER, DESA, Program director) c,⁎
Characteristics of a single versus multipleinjection axillary brachial plexus block (525 Ko) Sina Grape, Kyle Robert Kirkham and Eric Albrecht
Transversus abdominis plane block versus local anesthetic wound infiltration for optimal analgesia after laparoscopic cholecystectomy: A systematic review and meta-analysis with trial sequential analysis (908 Ko) Sina Grape a,*, Kyle Robert Kirkham b, Liliane Akiki c, Eric Albrecht d
Transversus abdominis plane block versus local anaesthetic wound infiltration for analgesia after caesarean section (342 Ko) A systematic review and meta-analysis with trial sequential analysis Sina Grape, Kyle Robert Kirkham and Eric Albrecht
The analgesic efficacy of transversus abdominis plane block vs. wound infiltration after inguinal and infraumbilical hernia repairs (1 Mo) Sina Grape, Kyle R. Kirkham and Eric Albrecht
Impact of an extrafascial versus intrafascial injection for supraclavicular brachial plexus block on respiratory function: a randomized, controlled, double-blind trial (505 Ko) Sina Grape ,1,2 Kyle Kirkham,3 Nadjib Zemirline,1 Alexis Bikfalvi,4 Eric Albrecht 2,4
Intravenous dexamethasone for prophylaxis of postoperative nausea and vomiting after administration of long-acting neuraxial opioids: a systematic review and meta-analysis (942 Ko) S. Grape,1 I. Usmanova,2 K. R. Kirkham3 and E. Albrecht4
Reversible cerebral vasoconstriction syndrome during caesarean section (305 Ko) Szilard Laszlo Safran,1,2 Christian Balmer,1 Georges Savoldelli 2,3 1 Service d’anesthésiologie et de réanimation du CHVR, Hopital du Valais, Sion, Switzerland 2 Department of Anaesthesiology, Clinical Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals,Geneva, Switzerland 3 Department of Anaesthesiology,Clinical Pharmacology, Intensive Care and Emergency Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland